Why did they discontinue Midrin?
Why did they discontinue Midrin?
Why was Midrin discontinued? Midrin contains isometheptene, which has been on the market for a very long time, since the time when the FDA approved medications only based on safety, and not effectiveness.
What took the place of Midrin?
Dichloralphenazone is a mild sedative that helps reduce a patient’s emotional response to painful stimuli. Another commercial product, Prodrin®, which has also been discontinued, is a similar medication that contains two of the three ingredients found in Midrin®, plus caffeine.
When did they stop making Midrin?
Midrin was discontinued by Caraco Pharmaceuticals as of 2009, after an FDA seizure of 33 drugs manufactured by Caraco Pharmaceuticals due to cGMP (Current Good Manufacturing Practices) violations. Generic forms of Amidrine were also discontinued due to loss of FDA grandfather approval status.
Is Midrin a triptan?
Imitrex and Midrin belong to different drug classes. Imitrex is a selective serotonin receptor agonist (also called a triptan) and Midrin is a combination of a pain reliever and fever reducer, a sedative, and a vasoconstrictor.
Is Midrin a narcotic?
The DEA received a formal request from Elan Pharmaceuticals for an exemption for Midrin® as an exempt non-narcotic prescription product.
What is generic for Midrin?
GENERIC NAME: ISOMETHEPTENE/ ACETAMINOPHEN/ DICHLORALPHENAZONE – ORAL (a-SEET-a-MIN-oh-fen/EYE-soe-meth-EP-teen/ DYE-klor-al-FEN-a-zone)
Is Midrin addictive?
Intranasal dihydroergotamine (DHE) (Migranal) is also a potential option. Combination agents such as Midrin, Fioricet, and agents containing caffeine such as Excedrin, should be used sparingly and provided in limited amounts to avoid dependence.
Does Midrin make you sleepy?
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.