What is muscle gene expression?
What is muscle gene expression?
Muscle has an intrinsic ability to change its mass and phenotype in response to activity. This process involves quantitative and qualitative changes in gene expression, including that of the myosin heavy chain isogenes that encode different types of molecular motors.
How are genes expressed in a muscle cell?
Smooth muscle cells (SMCs) perform a unique contractile function through expression of specific genes controlled by serum response factor (SRF), a transcription factor that binds to DNA sites known as the CArG boxes.
What is specific gene expression?
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect.
What detects the expression of specific genes?
When studying gene expression with real-time polymerase chain reaction (PCR), scientists usually investigate changes – increases or decreases – in the expression of a particular gene or set of genes by measuring the abundance of the gene-specific transcript.
Do muscle cells express different genes?
In fact, there is a common set of genes to which they can both bind, but differences between their DNA-binding regions allow each of the two proteins to also turn on their own unique sets of genes, which is what enables one to make muscle cells while the other makes neurons.
How many genes are in a muscle cell?
About 400 genes, highly expressed in skeletal muscle or putatively skeletal muscle-specific, may represent the minimal set of genes needed to determine the tissue specificity.
What causes tissue specific gene expression?
Characterizing Relationships between Tissue-Specific Network Elements. We tend to think about tissue specificity in terms of gene expression. However, we know that gene expression arises from a complex set of regulatory interactions between transcription factors and their target genes.
How does tissue specific gene expression work?
Tissue-specific gene expression provides one mechanism by which the same genome can generate differentiated phenotypes among tissues. In our dataset, uniquely expressed genes were largely considered typical for each tissue.
What is gene expression and why is it important?
Gene expression is a tightly regulated process that allows a cell to respond to its changing environment. It acts as both an on/off switch to control when proteins are made and also a volume control that increases or decreases the amount of proteins made.
Do muscle cells and nerve cells express different genes?
Why do muscle cells differ from nerve cells?
Nerve cells are functional units of the nervous system that are always involuntary. Muscle cells are found specifically in muscles and possess the ability to shorten themselves due to the presence of motor proteins in them. Nerve cells are functional units of the nervous system.