Is propylene glycol a safe ingredient?

Is propylene glycol a safe ingredient?

Propylene glycol is “generally recognized as safe” (GRAS) by the US Food and Drug Administration (FDA) ( 8 ). In the US, it can be used as a direct and indirect food additive.

Is propylene glycol a carcinogen?

The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the EPA have not classified propylene glycol for carcinogenicity. Animal studies have not shown this chemical to be carcinogen.

Is propylene glycol a neurotoxin?

These are the most commonly found neurotoxic cosmetic ingredients along with the basics of what you’ll want to know about them. Because it is readily and easily absorbed into the skin, propylene glycol is an ingredient to avoid.

Is propylene glycol safe to use on skin?

Is propylene glycol safe for skin? Propylene glycol is a humectant, which means that it is an ingredient that is added to cosmetics to increase moisture retention in skin and hair. Propylene glycol is well tolerated by the skin and shouldn’t cause redness or irritation.

What percentage of propylene glycol and is it safe?

50.0%
A safety assessment of propylene glycol (PG) and polypropylene glycols (PPGs) was published in 1994. On the basis of the available data, the Cosmetic Ingredient Review (CIR) Expert Panel concluded that these ingredients were safe for use in cosmetic products at concentrations up to 50.0%.

How long does it take to get propylene glycol out of your system?

about 48 hours
Propylene glycol breaks down in the body in about 48 hours. However, studies of people and animals show that if you have repeated eye, skin, nasal, or oral exposures to propylene glycol for a short time, you may develop some irritation.

How does propylene glycol affect the brain?

PG produced a striking increase in AC-3-positive cells throughout the brain ( Figure 1 ), as compared to saline-treated animals. The most severely affected areas were the caudate/putamen (CPu) and cortical regions (especially the retrosplenial, cingulate, and motor cortex).

Can propylene glycol be absorbed through skin?

Let me be clear: propylene glycol is one of the ingredients that penetrates skin but “absorption through the skin is minimal.” Since PG itself is safe to ingest (it’s either excreted in the urine or it breaks down in the blood to form lactic acid, which is naturally produced by your body, toxicity isn’t really an issue …

Is propylene glycol banned in Europe?

The European authorities responsible for consumer health have approved the use of propylene glycol with food: in direct food contact regulated by Regulation (EC) No 1333/2008 on food additives: Propane- 1,2-diol (propylene glycol USP/EP) is listed as an approved food additive in Annexes II+III under E1520.