What does flowability mean?
What does flowability mean?
Definition of flowability : the capacity to move by flow that characterizes fluids and loose particulate solids.
How is Hausner ratio calculated?
The Hausner ratio6 expressed as the tap density divided by the bulk density, Hr = ρtap/ρb, and related Carr index,7 CI = 1 − 1/Hr, are used to indicate the flowability of granular powders in a wide variety of industries.
How do you calculate powder flowability?
Some of the most commonly applied methods to measure the flow of powders include: density indices, such as the Carr index and Hausner ratio, powder avalanching, the angle of repose (AOR), flow through an orifice, powder rheometry and shear cell testing.
What are the important factors on which the flowability of solids depends?
Moisture content, temperature, particle size, and time of storage at rest can have a tremendous impact on your material’s flow properties.
What is Glidant in pharmaceuticals?
Glidants are additive substances that are used to enhance the flowability of a powder by reducing the interparticle friction, surface charge, and cohesion, which in turn decreases the angle of repose.
What is flowability casting?
” Flowability ” is a property of sand mix which influences the production of moulds of uniform hardness and density and consequently castings flee from defects such as expansion and erosion scabs.
What is compressibility index and Hausner ratio?
The compressibility index and the Hausner ratio are determined by measuring both the bulk volume and the tapped volume of a powder.
What is the Carr’s index formula?
Carr Index of any solid is calculated for compressibility of a powder which is based on true density (ρT) and bulk density (ρB), CI=100[(ρT‒ρB)/ρB]. A Carr index greater than 25 is considered to be an indication of poor flowability, and below 15, of good flowability.
How does particle size affect flowability?
Particle Size Very fine particles possess attractive forces such as Van Der Waals, electrostatics, surface tension etc. and resulting cohesion of powder and poor flow properties. As particle size increases, flow of the powders also increases and after certain level works as free flowing.
What is difference between glidant and lubricant?
Lubricants are substances that we use in tablet and capsule formulations in order to reduce the friction. More importantly, these substances reduce the friction between particles that we use to make the tablet during compression. Glidants are substances that we use to increase the flowability of a powder.
What is disintegrating agent?
A disintegrating agent and a swelling agent are used in combination with coated drug particles in this formulation to produce a tablet that disintegrates in the mouth in less than one minute (Gauri and Kumar, 2012). From: Drug Delivery Systems, 2019.