Can sulfasalazine affect the heart?

Can sulfasalazine affect the heart?

Very bad and sometimes deadly allergic reactions, infections, heart problems, kidney problems, liver problems, lung problems, and blood problems have happened with this medicine (sulfasalazine tablets).

What do you monitor with sulfasalazine?

You’ll need blood tests and liver and kidney tests before you start treatment with sulfasalazine, and then regular monitoring tests. The most common side effects of sulfasalazine are indigestion and feeling sick. Drink plenty of fluids when taking sulfasalazine to help prevent possible kidney problems.

Can sulfasalazine cause increased heart rate?

Call your doctor right away if you have difficulty breathing or swallowing, a fast heartbeat, itching, rash, or skin redness, or swelling of the face, throat, or tongue. These may be symptoms of an allergic reaction to this medicine.

Can sulfasalazine affect blood pressure?

Effect of Sulfasalazine on Vascular Function In addition, we found no effect of sulfasalazine on blood pressure, hyperemic response, or arterial diameter. There was no evidence of an effect of treatment order for any of the vascular measures.

Does sulfasalazine reduce ESR?

Morning stiffness and the erythrocyte sedimentation rate/’sed’ rate (ESR) decreased more in people taking sulfasalazine compared to those taking fake pills (lower ESRs usually mean less inflammation).

Can sulfasalazine cause high MCV?

In IBD, however, the use of sulphasalazine at daily doses higher than 2 g leads to further increases in MCV and reduction of red cell folate concentrations (1, 9).

What’s the side effects of sulfasalazine?

The most common side effects of sulfasalazine are:

  • feeling or being sick.
  • heartburn.
  • diarrhoea.
  • stomach pain.
  • dizziness.
  • difficulty sleeping.
  • cough.
  • joint pain.

Does sulfasalazine cause high blood pressure?

Does sulfasalazine cause high blood pressure? Sulfasalazine has not been found to be associated with high blood pressure (hypertension) in a clinical research study. Also, the manufacturer’s product information does not list high blood pressure as a side effect.

Does sulfasalazine increase cholesterol?

A decrease in disease activity with either methotrexate plus etanercept or triple therapy with methotrexate, sulfasalazine and hydroxychloroquine concomitantly was associated with an increase in HDL levels, lower LDL levels and a lower total cholesterol-to-HDL levels, according to recently published research.