What are SW620 cells?

What are SW620 cells?

SW620 [SW-620] cells are isolated from the large intestine of a 51-year-old male Dukes C colorectal cancer patient. The cells can be used for cancer and toxicology research and high-throughput screening. Homo sapiens, human. Morphology epithelial Tissue Large intestine; Colon Disease.

What are ht29 cells?

HT-29 is a human colorectal adenocarcinoma cell line with epithelial morphology. These cells are sensitive to the chemotherapeutic drugs 5-fluorouracil and oxaliplatin, which are standard treatment options for colorectal cancer.

Where is HEK293 from?

Human embryonic kidney 293 cells, also often referred to as HEK 293, HEK-293, 293 cells, or less precisely as HEK cells, are a specific immortalised cell line derived from a spontaneously miscarried or aborted fetus or human embryonic kidney cells grown in tissue culture taken from a female fetus in 1973.

What is the difference between HEK293 and HEK293T?

The key difference between HEK293 and HEK293t is that HEK293 is an immortalized cell line derived from the embryonic human kidney that is transfected with sheared human adenovirus type 5DNA while HEK293t is a daughter cell line derived from HEK293 original cell line that is transfected with a plasmid vector carrying …

What is the difference between 293 and 293T cells?

The 293T cells are derived from 293 cells but stably express the SV40 large T antigen which can bind to SV40 enhancers of expression vectors to increase protein production. 293T are also neomycin resistant due to the presence of a neomycin resistance cassete together with the SV40 Large T .

What has HEK293 been used for?

HEK293 cells are used in cancer research, vaccine development, protein production, signal transduction and protein interaction studies, drug testing, and receptor de-orphanization, just to list a few!

Where did HEK293 cells come from?

Originating from a female fetus, HEK293 cells are today among the most used mammalian cell lines for a wide range of applications because of their ease of transfection as well as culture. Despite stemming from kidney tissue, HEK293 cells – time and time again – exhibited properties of immature neurons.

What are HEK-293 cells used for?

The human embryonic kidney (HEK) 293 cell line and its derivatives are used in experiments ranging from signal transduction and protein interaction studies over viral packaging to rapid small-scale protein expression and biopharmaceutical production.