What does endocervical and squamous metaplastic cells present mean?
What does endocervical and squamous metaplastic cells present mean?
The phrase “endocervical cells present” simply means that your doctor sampled cells from the inside of your cervix during the Pap smear. The phrase “squamous metaplastic cells present” means that the pathologist who examined your Pap smear found cells that were growing and repairing themselves regularly.
Does squamous metaplasia mean cancer?
Squamous metaplasia is a benign non-cancerous change (metaplasia) of surfacing lining cells (epithelium) to a squamous morphology.
What causes squamous metaplasia in the cervix?
Factors in the initiation and promotion of squamous metaplasia are chronic irritation of a physical nature, such as that caused by an intrauterine contraceptive device (IUD), chemical irritants, inflammation with cell destruction, and endocrine changes at the beginning of, during, and after reproductive age.
What is a squamous metaplasia?
Squamous metaplasia, the process by which mature, non-squamous epithelium is replaced by stratified squamous epithelium, is a well-described phenomenon in the endocervical canal of both women and laboratory animals.
How often does metaplasia turn into cancer?
Atrophic gastritis, intestinal metaplasia, mild-moderate dysplasia, and severe dysplasia were associated with annual incidences of gastric cancer of 0.1%, 0.25%, 0.6%, and 6.0%, respectively.
Should I worry about squamous metaplasia?
There is no risk of malignant transformation for squamous metaplasia. Nevertheless, the metaplastic change within the endocervix may increase the risk for human papilloma virus infection (Hwang et al., 2012), which is a risk factor for cervical cancer.
Is squamous mucosa normal?
The mucosa of the normal esophagus is composed of squamous cells similar to those of the skin or mouth. The normal squamous mucosal surface appears whitish-pink in color, contrasting sharply with the salmon pink to red appearance of the gastric mucosa, which is composed of columnar cells.
Is squamous metaplasia normal?
There are two types of squamous metaplasia of the urothelium, nonkeratinizing and keratinizing. The former is considered as a normal finding in females, present in the trigone and bladder neck in up to 85% of women of reproductive age and 75% of postmenopausal women.
Is squamous metaplasia painful?
The causes of pain in squamous metaplasia of the bladder are unknown. The pain is usually attributed to the disruption of the layer of glycosaminoglycans (GAGs, compounds of composite structure, having a negative charge) covering the urothelium.