What does pol II do?
What does pol II do?
Eukaryotic RNA polymerase II (pol II) is a 12-subunit DNA-dependent RNA polymerase that is responsible for transcribing nuclear genes encoding messenger RNAs and several small nuclear RNAs (1).
What does RNA pol 5 do?
RNA polymerase V (Pol V), previously known as RNA polymerase IVb, is a multisubunit plant specific RNA polymerase. It is required for normal function and biogenesis of small interfering RNA (siRNA).
What is the difference between RNA Pol I and Pol III?
RNA polymerase I (RNAPI) transcribes rRNA genes, RNA polymerase II (RNAPII) transcribes mRNA, miRNA, snRNA, and snoRNA genes, and RNA polymerase III (RNAPIII) transcribes tRNA and 5S rRNA genes. This is in contrast with prokaryotes where a single RNA polymerase is responsible for the transcription of all genes.
What is the function of DNA polymerase I?
DNA polymerase I of eubacteria functions in vivo to synthesize short stretches of DNA during excision repair and to remove RNA primers and fill the gaps between Okazaki fragments in lagging strand replication.
What would happen if RNA polymerase is not working properly?
If RNA polymerase malfunctions, one of the subunits of rRNA will not be transcribed from DNA. amino acids will not be joined to their tRNA. mRNA cannot bind to rRNA.
Where is RNA polymerase 2 found?
the nucleus
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. It is one of the three RNAP enzymes found in the nucleus of eukaryotic cells.
What is the difference between polymerase 1 and 2?
DNA polymerase 1, 2 and 3 are prokaryotic DNA polymerases involved in DNA replication. Pol 1 catalyzes the repairing of DNA damages. Pol 2 catalyzes the fidelity and processivity of DNA replication.
What does DNA pol I do?
DNA polymerase is responsible for the process of DNA replication, during which a double-stranded DNA molecule is copied into two identical DNA molecules. Scientists have taken advantage of the power of DNA polymerase molecules to copy DNA molecules in test tubes via polymerase chain reaction, also known as PCR.
What would happen without DNA polymerase 1?
DNA polymerase I is strikingly important for survival of the cell following many types of DNA damage, and in its absence, the cell has persistent single-stranded breaks that promote DNA recombination.