What is a pharmaceutically acceptable salt?

What is a pharmaceutically acceptable salt?

pharmaceutically acceptable salt of a compound means a salt that is pharmaceutically acceptable and that possesses the desired pharmacological activity of the parent compound.

Which salts are used in medicine?

Over 50% of all drug molecules used in medicine exist as salts, most frequently as the hydrochloride, sodium, or sulfate salts. Drugs are often formed as a weak acid or base, but this drug form is not always optimal for dissolution or absorption into your body.

What are the importance of salt in pharmacy?

The formation of salts is invaluable for the preparation of safe and effective dosage forms of many drugs [1], [2], [3]. Whether the drug products are solutions or solids, the use of a salt provides a higher concentration in solution than the free acid or free base (nonionized forms).

What is a hydrochloride salt?

Hydrochloride (hydrochloride salt): A salt consisting of a chloride anion with the conjugate acid cation of a base, usually an amine. The generic structure is B-H+ Cl-. + H-Cl. Pyridine.

What is good solubility for a drug?

A drug is considered highly soluble when the highest dose strength is soluble in 250 mL or less of aqueous media over the pH range of 1 to 7.5.

Which salt is used mostly in pharma industry Mcq?

Explanation: Common Salt that is Sodium Chloride is used as a raw material for making a large number of useful chemicals in industry.

What are the types of salts?

5 Types of Salt and How They Affect Health

  • Refined Salt. Refined salt, also referred to as table salt or cooking salt, is originally produced from either salt mines or evaporated ocean water.
  • Sea Salt.
  • Kosher Salt.
  • Pink Himalayan Salt.
  • Celtic Salt.

What are the 10 uses of salt?

10 good uses for salt

  • Deter ants.
  • Kill grass and weeds growing in cracks in your driveway.
  • Say goodbye to fleas.
  • Pick up a dropped egg.
  • Clean up oven spills quickly.
  • Clean brown spots off your iron.
  • Remove stains from your coffee pot.
  • Keep your windshield frost-free.

What is use salt?

Salt has long been used for flavoring and for preserving food. It has also been used in tanning, dyeing and bleaching, and the production of pottery, soap, and chlorine. Today, it is widely used in the chemical industry.

Is hydrochloride the same as hydrochloride?

Hydrochloride is an acid salt that originates from the reaction of hydrochloric acid with an organic base while dihydrochloride is a chemical compound consisting of two molecules of hydrochloric acid components associated with the same chemical species.

What are the 4 factors affecting solubility?

Factors affecting solubility

  • Temperature. Basically, solubility increases with temperature.
  • Polarity. In most cases solutes dissolve in solvents that have a similar polarity.
  • Pressure. Solid and liquid solutes.
  • Molecular size.
  • Stirring increases the speed of dissolving.