What is acetylcysteine solution used for?
What is acetylcysteine solution used for?
When inhaled by mouth, acetylcysteine is used to help thin and loosen mucus in the airways due to certain lung diseases (such as emphysema, bronchitis, cystic fibrosis, pneumonia). This effect helps you to clear the mucus from your lungs so that you can breathe easier.
How do you use Hidonac?
Adult Initial dose: 150 mg/kg in 200 mL of 5% glucose inj over 15 min. 2nd dose: 50 mg/kg in 500 mL of 5% glucose at slow infusion rate for 4 hr. 3rd dose: 100 mg/kg in 1 L of 5% glucose over 16 hr. Bronchial asthma, peptic ulceration, monitor coagulation factors.
How should acetylcysteine be diluted?
Dilute each 10 mL ampoule of N-acetylcysteine (200 mg/mL) with 310 mL glucose 5% or sodium chloride 0.9% to give a total volume of 320 mL. Any unused solution should be disposed of in accordance with local requirements.
How long does acetylcysteine take to work?
In humans peak plasma levels of acetylcysteine are reached in approximately 1-3 hours after an oral dose.
How many mg of acetylcysteine are in 1 mL of hidonac?
Each mL of solution contains 200 mg acetylcysteine, Ph. Eur. Acetylcysteine (HIDONAC) is a clear, colorless solution with a slightly sulphureous odor.
Can acetylcysteine 10% solution be used undiluted?
The 10% solution may be used undiluted. Acetylcysteine does not contain an antimicrobial agent, and care must be taken to minimize contamination of the sterile solution. If only a portion of the solution in a vial is used for inhalation, store the remainder in a refrigerator and use within 96 hours.
How do you take acetylcysteine?
Acetylcysteine is sterile, not for injection and can be used for inhalation (mucolytic agent) or oral administration (acetaminophin antidote). It is available as follows: Acetylcysteine 20% solution (200 mg acetylcysteine per mL).
What is acetylcysteine solution USP used for?
Acetylcysteine Solution, USP is indicated as adjuvant therapy for patients with abnormal, viscid, or inspissated mucous secretions in such conditions as: Chronic bronchopulmonary disease (chronic emphysema, emphysema with bronchitis, chronic asthmatic bronchitis, tuberculosis, bronchiectasis and primary amyloidosis of the lung)