What is glycated serum protein?
What is glycated serum protein?
Glycated serum proteins (GSP) are proteins within the body that have undergone glycation and circulate in the blood. The large majority (90%) of GSP consists of glycated albumin (GA) [4.
What is glycated serum protein GSP?
GSP is the amount of glucose attached to total serum proteins that indicate the average amount of glucose in the blood over the previous two to three weeks.
What is the normal value of glycated serum protein?
A serum fructosamine (a glycated protein) level, similar to a hemoglobin A1c (HbA1c) level, enables assessment of long-term glycemic control in patients with diabetes mellitus. Normal values vary in relation to the serum albumin concentration and are 200-285 µmol/L when the serum albumin concentration level is 5 g/dL.
What causes glycation?
Glycation is a process which is caused by the presence of excess glucose in skin fibers. This excess triggers an internal reaction in which sugar molecules adhere to the collagen and elastin proteins, which normally help keep skin firm and supple.
What can affect fructosamine levels?
However, several health conditions can affect a fructosamine test result. These include: Cirrhosis and other liver diseases. Certain kidney diseases.
What is fructosamine test?
What is being tested? Fructosamine is a compound that is formed when glucose combines with protein. This test measures the total amount of fructosamine (glycated protein) in the blood. Glucose molecules will permanently combine with proteins in the blood in a process called glycation.
How can I reduce glycation in my body?
Reducing the Effects of the Glycation Process
- Change Your Diet. Adopting an anti-AGE diet that’s rich in antioxidants and vitamins may be the most significant step you take in halting protein glycation and damage of vascular cells.
- Exercise Regularly.
- Stay Away From Tobacco Smoke.
- Up Your Carnosine Intake.
Which is an example of glycation?
Glycation has been implicated in neurodegenerative disease. For example, it has been shown that AGEs are present in affected regions of Alzheimer’s disease such as senile plaques, and neurofibrillary changes. Glycation has also been implicated in the pathogenesis of familial amyotrophic lateral sclerosis (FALS).