What is non compacted cardiomyopathy?
What is non compacted cardiomyopathy?
Non-compaction cardiomyopathy (NCM) is a myocardial disorder, which is thought to occur due to the failure of left ventricle (LV) compaction during embryogenesis, leading to distinct morphological characteristics in the ventricular chamber.
What causes non-compaction cardiomyopathy?
Left ventricular non-compaction cardiomyopathy causes In some people, the cause of LVNC is from changes in specific genes (mutations). These gene changes can affect how the heart forms and can lead to left ventricular non-compaction cardiomyopathy. These gene changes can be inherited from parent to child.
Is LVNC heart failure?
Even with a normal heart rhythm, some people with LVNC may develop heart muscle weakness that places them at risk for heart failure.
Is non compaction cardiomyopathy reversible?
The compacted myocardium in LVNC is approximately 30% thinner than normal. Accordingly, although transient or irreversible dilative evolution can develop during the life of a patient with LVNC, in all probability this congenital anomaly will never disappear.
Can LVNC be reversed?
I also exclude the biological possibility of de novo LVNC and its later disappearance because the structural changes in LVNC (intertrabecular recesses with endothelial lining, and trabecular structures with peculiar myocardial vascularization15) are not reversible after birth.
Is Left ventricular non compaction hereditary?
LVNC is largely a genetic condition. When an individual is diagnosed with LVNC, there is a 20 to 40 percent chance than an underlying genetic cause will be identified. Most commonly, the genetic cause results in a condition that runs in a family and affects only the heart.
How serious is LVNC?
Although some people with LVNC experience no symptoms, they may still be at risk for complications associated with the diagnosis. The most serious complication of LVNC is sudden cardiac arrest.