What is Zalmoxis?
What is Zalmoxis?
Zalmoxis (Greek: Ζάλμοξις) is a divinity of the Getae and Dacians (a people of the lower Danube), mentioned by Herodotus in his Histories Book IV, 93–96, written before 425 BC. Zalmoxis. Occupation. Scholar.
Who is the Thracian king?
Cersobleptes, (died 342 bc), King of Thrace (360–342). He inherited a war with Athens and was opposed internally by two pretenders to the throne.
Where did the Dacians come from?
The Dacians (/ˈdeɪʃənz/; Latin: Daci [ˈd̪aːkiː]; Greek: Δάκοι, Δάοι, Δάκαι) were the ancient Indo-European inhabitants of the cultural region of Dacia, located in the area near the Carpathian Mountains and west of the Black Sea.
Why was Zalmoxis withdrawn?
Most recently, Zalmoxis was withdrawn in October 2019 after unfavorable results reported from the post-approval phase III clinical trial,3 a requirement for conditional MA, which was obtained in 2016.
Is Zalmoxis a gene therapy?
Zalmoxis is constituted of donor’s T lymphocytes genetically modified to express the HSV-TK Mut2, as suicide gene. This allows the selective killing of dividing cells upon administration of the pro-drug GCV, which is enzymatically phosphorylated to an active triphosphate analogue by HSV-TK.
What is Thrace called today?
Thracian
Today, Thracian is a geographical term used in Greece, Turkey, and Bulgaria.
How did the Dacians look like?
The Dacian men were hefty with rugged features, wore beards and long hair, while the Dacian women were beautiful with stiff, severe but expressive features.
Who is Zamolxis?
Zamolxis (or Zamolxe) was the supreme deity of the Dacians, god of life and death.
What is Zynteglo used for?
Zynteglo is a medicine used to treat a blood disorder known as beta thalassaemia in patients 12 years and older who require regular blood transfusions. People with this genetic condition cannot make enough beta-globin, a component of haemoglobin, the protein in red blood cells that carries oxygen around the body.
Who is Zalmoxis in the Iliad?
Herodotus asserts that Zalmoxis was originally a human being, a slave who converted the Thracians to his beliefs. The Greeks of the Hellespont and the Black Sea tell that Zalmoxis was a slave of Pythagoras, son of Mnesarchos, on the island of Samos. After being liberated, he gathered huge wealth and, once rich, went back to his homeland.
What is Zalmoxis made of?
Zalmoxis contains T cells (a type of white blood cell) that have been genetically modified1. To make Zalmoxis, T cells from the HSCT donor are separated from the rest of the cells in the transplant. These T cells are then genetically modified to include a ‘suicide gene’.
Is Zalmoxis the same as Sabazius?
Aristotle is said, in the brief epitome of his Magicus given by Diogenes Laertes, to have compared Zalmoxis with the Phoenician Okhon and Libyan Atlas. Some authors assume Zalmoxis was another name of Sabazius, the Thracian Dionysus, or Zeus. Sabazius appears in Jordanes as Gebelezis.
Is Zalmoxis an orphan medicine?
Because the number of patients undergoing haploidentical HSCT is low, Zalmoxis was designated an ‘orphan medicine’ (a medicine used in rare diseases) on 20 October 2003 by the EMA. Zalmoxis is developed by MolMed S.p.A and the product has been given ‘conditional approval’ by the European Medicines Agency (EMA) in September 2016.