What medications can cause pigmentation?

What medications can cause pigmentation?

Pigmentation may be induced by a wide variety of drugs; the main ones implicated include non-steroidal anti-inflammatory drugs (NSAIDs), phenytoin, antimalarials, amiodarone, antipsychotic drugs, cytotoxic drugs, tetracyclines, and heavy metals.

How long does drug-induced pigmentation last?

Antineoplastic Agents Cyclophosphamide can cause hyperpigmented patches after the fourth week of treatment, which disappear 6 to 12 months after treatment cessation and may seem on the palms, soles, nails, teeth, and, rarely, on the gums.

What medications cause melasma?

Phototoxic drugs (medicines that make you sensitive to sunlight): These include some antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), diuretics, retinoids, hypoglycaemics, antipsychotics, targeted therapies and some other drugs.

How is drug induced hyperpigmentation treated?

Treatment / Management [3] In these cases, decreasing the intake of a drug can dramatically reduce the dyschromia present. Additionally, specific drug-induced pigmentation is avoidable by limiting sun exposure. These drugs include antimalarials, psychotropic, amiodarone, and tetracyclines.

Can medication cause dark spots on face?

Medication side effects Certain medications can increase skin pigmentation and lead to dark spots. The most common culprits are non-steroidal anti-inflammatory drugs (NSAIDs), tetracyclines, and psychotropic drugs.

What medications cause dark spots on skin?

Certain medications can increase skin pigmentation and lead to dark spots. The most common culprits are non-steroidal anti-inflammatory drugs (NSAIDs), tetracyclines, and psychotropic drugs.

Can drugs cause brown spots on skin?

Drug-induced pigmentation is a form of abnormal skin pigmentation that is caused by drugs through several different mechanisms. Several drugs have associations with pigmentation, including cytotoxic agents, analgesics, anticoagulants, antimicrobials, antiretrovirals, metals, and antiarrhythmic, etc.

Can antidepressants cause pigmentation?

Conclusions: Psychotropic drugs associated with cutaneous hyperpigmentation include amitriptyline, chlorpromazine, citalopram, desipramine, imipramine, mirtazapine, phenytoin, sertraline, and thioridazine. The hyperpigmentation may initially appear many years after starting the medication.

Does vitamin C lighten pigmentation?

Might Lighten Dark Spots Vitamin C-based skin care products may lighten patches that are darker than the rest of your skin, called hyperpigmentation. In one study, vitamin C applied to the skin for 16 weeks significantly cut down on these spots.